Prof. Jie Wen
Author:臧晶晶  Release time:2020-05-29   Access times:594


Jie Wen 


The First Affiliated Hospital of USTC

CAS Key Laboratory of Microscale Magnetic Resonance








University of Science and Technology of China
Applied Physics


University of Science and Technology of China
Structural Biology


Washington University in St. Louis

RadiologyPostdoctoral Research Associate


National Multiple Sclerosis Society

Postdoctoral Fellow


Washington University in St. Louis

Radiology, Instructor


University of Science and Technology of China

The First Affiliated HospitalProfessor



  1. Quantitative magnetic resonance imaging and its clinical applications

  2. Molecular imaging method

  3. MRI image analysis and processing




Targeted MRI based on cyanobacteria gas vesicle”, Joint fund of "USTC New Medicine", PI



  1. Xiang, B., Wen, J., Lu, H.C., Schmidt, R.E., Yablonskiy, D.A., Cross, A.H., In vivo evolution of biopsy-proven inflammatory demyelination quantified by R2t* mapping. Ann Clin Transl Neurol. 2020. doi: 10.1002/acn3.51052.

  2. Xiang, B., J. Wen, A.H. Cross, and D.A. Yablonskiy, Single scan quantitative gradient recalled echo MRI for evaluation of tissue damage in lesions and normal appearing gray and white matter in multiple sclerosis. J Magn Reson Imaging, 2019. 49(2): p. 487-498.

  3. Astafiev, S.V., J. Wen, D.L. Brody, A.H. Cross, A.P. Anokhin, K.L. Zinn, M. Corbetta, and D.A. Yablonskiy, A Novel Gradient Echo Plural Contrast Imaging Method Detects Brain Tissue Abnormalities in Patients With TBI Without Evident Anatomical Changes on Clinical MRI: A Pilot Study. Mil Med, 2019. 184(Suppl 1): p. 218-227.

  4. Wen, J., M.S. Goyal, S.V. Astafiev, M.E. Raichle, and D.A. Yablonskiy, Genetically defined cellular correlates of the baseline brain MRI signal. Proc Natl Acad Sci U S A, 2018. 115(41): p. E9727-E9736.

  5. Wen, J., A.L. Sukstanskii, and D.A. Yablonskiy, Phase-sensitive B1 mapping: Effects of relaxation and RF spoiling. Magn Reson Med, 2018. 80(1): p. 101-111.

  6. Cai, B., S.M. Goddu, S. Yaddanapudi, D. Caruthers, J. Wen, C. Noel, S. Mutic, and B. Sun, Normalize the response of EPID in pursuit of linear accelerator dosimetry standardization. J Appl Clin Med Phys, 2018. 19(1): p. 73-85.

  7. Adusumilli, G., K. Trinkaus, P. Sun, S. Lancia, J.D. Viox, J. Wen, R.T. Naismith, and A.H. Cross, Intensity ratio to improve black hole assessment in multiple sclerosis. Mult Scler Relat Disord, 2018. 19: p. 140-147.

  8. Wen, J., D.A. Yablonskiy, A. Salter, and A.H. Cross, Limbic system damage in MS: MRI assessment and correlations with clinical testing. PLoS One, 2017. 12(11): p. e0187915.

  9. Sukstanskii, A.L., J. Wen, A.H. Cross, and D.A. Yablonskiy, Simultaneous multi-angular relaxometry of tissue with MRI (SMART MRI): Theoretical background and proof of concept. Magn Reson Med, 2017. 77(3): p. 1296-1306.

  10. Zhao, Y., M.E. Raichle, J. Wen, T.L. Benzinger, A.M. Fagan, J. Hassenstab, A.G. Vlassenko, J. Luo, N.J. Cairns, J.J. Christensen, J.C. Morris, and D.A. Yablonskiy, In vivo detection of microstructural correlates of brain pathology in preclinical and early Alzheimer Disease with magnetic resonance imaging. Neuroimage, 2017. 148: p. 296-304.

  11. Cai, B., H. Li, D. Yang, V. Rodriguez, A. Curcuru, Y. Wang, J. Wen, R. Kashani, S. Mutic, and O. Green, Performance of a multi leaf collimator system for MR-guided radiation therapy. Med Phys, 2017. 44(12): p. 6504-6514.

  12. Zhao, Y., J. Wen, A.H. Cross, and D.A. Yablonskiy, On the relationship between cellular and hemodynamic properties of the human brain cortex throughout adult lifespan. Neuroimage, 2016. 133: p. 417-429.

  13. Wen, J., D.A. Yablonskiy, J. Luo, S. Lancia, C. Hildebolt, and A.H. Cross, Detection and quantification of regional cortical gray matter damage in multiple sclerosis utilizing gradient echo MRI. Neuroimage Clin, 2015. 9: p. 164-75.

  14. Mamah, D., J. Wen, J. Luo, X. Ulrich, D.M. Barch, and D. Yablonskiy, Subcomponents of brain T2* relaxation in schizophrenia, bipolar disorder and siblings: A Gradient Echo Plural Contrast Imaging (GEPCI) study. Schizophr Res, 2015. 169(1-3): p. 36-45.

  15. Wen, J., A.H. Cross, and D.A. Yablonskiy, On the role of physiological fluctuations in quantitative gradient echo MRI: implications for GEPCI, QSM, and SWI. Magn Reson Med, 2015. 73(1): p. 195-203.

  16. Wen, J., Zhou, P., Wu, J., Efficient acquisition of high-resolution 4-D diagonal-suppressed methyl-methyl NOESY for large proteins. J Magn Reson, 2012. 218: p. 128-132.

  17. Wen, J., Wu, J., Zhou, P., Sparsely sampled high-resolution 4-D experiments for efficient backbone resonance assignment of disordered proteins. J Magn Reson, 2011. 209(1): p. 94-100.