A/Prof. Ruan Ke
.
Author:臧晶晶  Release time:2020-06-01   Access times:67

Name: 

Ruan Ke

Address:

Room 243, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, 230027, PR China

Tel:

0551-63607767

E-mail:

kruan(AT)ustc.edu.cn

 

EDUCATION AND RESEARCH EXPERIENCE

1995-1999

Peking University
B. S.
Chemistry

1999-2002

Peking University
M. S., Physical Chemistry

2002-2008

Johns Hopkins University

Ph. D., Biophysical Chemistry

2008-2010

Pfizer Inc.

Global R & D, postdoc

2010-2011

CRUK Beatson Institute

Drug Discovery Unit, Staff Scientist

 2011-present

University of Science and Technology of China

School of Life Sciences, Associate Professor


RESEARCH INTERESTS

Biomolecular NMR spectroscopy, Fragment-based Lead Discovery, Protein Dynamics.

 

CURRENT RESEARCH PROJECTS

1.

National R&D project (2016 & 2020)

2.

NSFC (2019)

 

REPRESENTATIVE PUBLICATIONS

  1. Xu D.#; Li B.#; Gao J.#; Liu Z.; Niu X.; Nshogoza G.; Zhang J.; Wu J.; Su X.-C.; He W.; Ma R.*; Yang D.*; Ruan K.*; Ligand Proton Pseudocontact Shifts Determined from Paramagnetic Relaxation Dispersion in the Limit of NMR Intermediate Exchange, Journal of Physical Chemistry Letters 9, 3361 (2018).

  2. Xu D.; Ma R.; Zhang J.; Liu Z.; Wu B.; Peng J.; Zhai Y.; Gong Q.; Shi Y.; Wu J.; Wu Q.; Zhang Z.*; Ruan K.*; Dynamic Nature of CTCF Tandem 11 Zinc Fingers in Multivalent Recognition of DNA as Revealed by NMR Spectroscopy, Journal of Physical Chemistry Letters 9, 4020 (2018).

  3. Gao, Jia#; Liang, E#; Ma, Rongsheng; Li, Fudong; Liu, Yixiang; Liu, Jiuyang; Jiang, Ling; Li, Conggang; Dai, Haiming; Wu, Jihui; Su, Xuncheng; He, Wei; Ruan, Ke*; Fluorine Pseudocontact Shifts Used for Characterizing the Protein-Ligand Interaction Mode in the Limit of NMR Intermediate Exchange, Angew Chem Int Ed Engl, 56): 12982 (2017).